Pentobarbital will lessen the extent or effect of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with strong CYP3A4 inducers is not proposed The outcome of barbiturates within the metabolism of phenytoin appears to be variable. Some investigators report an accelerating influence, while some report no outcome. https://solangeh556hzr7.blogginaway.com/profile