Investigate into conolidine has resulted in discovery of an opioid receptor in the human body known as ACKR3/CXCR7. ACKR3 seems to be quite possibly the most sought after focus on for conolidine, which also disregards the other four classical opioid receptors(3). Conolidine has been found in the tabernaemontana divaricata https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers