Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of buspirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of cevimeline by affecting hepatic/intestinal enzym... https://bookmarkport.com/story22895318/poco-conosciuto-fatti-circa-pentobarbital-natrium